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Calcipotriol

IUPAC name:

(1R,3S,5E)-5-{2-[(1R,3aS,4Z,7aR)-1-[(2R,3E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohyytyexane-1,3-diol

Trade name:Daivobex, Dovobex, Sorilux

CAS No.:112965-21-6

Molecular Formula: C27H40O3

Molar mass:412.605

Pharmacology action: This product is similar to vitamin D analogues, the pharmacodynamic properties and vitamin D3 active metabolite of Calcitriol. In several in vitro models of this product and Calcitriol significantly inhibit cell proliferation and stimulate cell differentiation, such as both reduce the number of cells, total DNA content and radiation labeled thymidine incorporation into DNA, increase human keratinocytes and enhance the activity of the protein cross-linking enzyme, inhibit the proliferation and differentiation of epidermal cells.

On a:Calcitriol

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Add:No.188,Linchang Road, Baima Town, Neijiang, Sichuan, China  蜀ICP備05031241號   Sichuan Neijiang Huixin Pharmacy Co.,Ltd.  All rights reserved.   Tel:0832-8781104  0832-5079510  0832-5079508   Fax:0832-8781144   

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